DIAGAMMA

Solution for injection, 2 ml

DIAGAMMA is a certified and officially registered medicinal product in Ukraine containing a combination of vitamins B1, B6, and B12. The product is intended for intramuscular injection and is supplied in ampoules as a red-colored solution.

Administration of this combination of B vitamins supports normal metabolism, enhances the production of neurochemical and signaling molecules, improves blood circulation, and contributes to the normal functioning of the nervous system. Scientific studies have shown that a significant proportion of the population in developed countries is deficient in one or more B vitamins. For this reason, some researchers believe that medicinal products containing vitamins B1, B6, and B12 may help improve brain health and central nervous system function in many patients.

Important! Due to the presence of lidocaine, an allergy test should be performed before administration. The medicinal product should not be prescribed to children. It should not be used during pregnancy or breastfeeding, as the doses of vitamins exceed the maximum recommended daily intake.

Composition:

Active substances: thiamine hydrochloride, pyridoxine hydrochloride, cyanocobalamin.
1 ml of solution contains: thiamine hydrochloride (calculated as 100% substance) 50 mg, pyridoxine hydrochloride (calculated as 100% substance) 50 mg, cyanocobalamin (calculated as 100% substance) 0.5 mg.

Excipients:

lidocaine hydrochloride, benzyl alcohol, sodium polyphosphate, potassium ferricyanide, sodium hydroxide, water for injections.

Dosage form:

Solution for injection.

Appearance:

clear red solution.

Pharmacotherapeutic group:

Vitamin B1 preparations in combination with vitamin B6 and/or vitamin B12.
ATC code: A11DB.

Shelf life:

2 years.

Storage conditions:

Store out of the reach of children.
Store in the original packaging at a temperature between 2°C and 8°C.

Incompatibility:

Thiamine is incompatible with oxidizing and reducing agents, including mercuric chloride, iodide, carbonate, acetate, tannic acid, iron ammonium citrate, as well as sodium phenobarbital, riboflavin, benzylpenicillin, glucose, and metabisulfite, since it is inactivated in their presence. Copper accelerates the degradation of thiamine. In addition, thiamine loses its activity when the pH exceeds 3.

Vitamin B12 is incompatible with oxidizing and reducing agents and with heavy metal salts.

In solutions containing thiamine, vitamin B12, like other B-complex vitamins, is rapidly degraded by thiamine degradation products (low concentrations of iron ions may protect against this effect). Riboflavin, especially when exposed to light, also promotes degradation, while nicotinamide accelerates photolysis. Antioxidants exert an inhibitory effect on these degradation processes.

Packaging:

2 ml in an ampoule; 5 ampoules in a blister pack; 1 blister pack in a carton.

Prescription status:

Prescription only.

Manufacturer:

Private Joint Stock Company “Lekhim-Kharkiv”.

Manufacturer’s location and address of the manufacturing site:

36 Severyna Pototskoho St., Kharkiv, Kharkiv Region, 61115, Ukraine.

For detailed information, please refer to the Instructions for Medical Use.

Information on medicinal products is intended exclusively for healthcare professionals.