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PRODUCT

TENIKAM

GENERAL INFORMATION

TENIKAM is a medicine containing tenoxicam and belongs to the group of non-steroidal anti-inflammatory drugs.

TENIKAM – refers to the oxicam group NSAIDs and has a pronounced analgesic, anti-inflammatory and some antipyretic effect.

Tenoxicam mechanism of action is inhibition of the enzyme cyclooxygenase, which ensures the conversion of arachidonic acid into prostaglandins, both in the focus of inflammation and in other tissues of the body. Tenoxicam also has the ability to inhibit the formation of oxygen radicals, inhibit phagocytosis and chemotaxis of leukocytes, and also has antiplatelet properties. In addition to acting in the focus of inflammation, tenoxicam also acts on the thalamic centers of pain sensitivity. Tenoxicam is a non-selective inhibitor of cyclooxygenases, and equally acts on isoforms of cyclooxygenase — COX-1 and COX-2.

TENICAM in the form of a lyophilizate is a long-acting drug, the administration of a dose once a day is effective. The average plasma half-life is approximately 72 hours. After intravenous administration of tenoxicam in a dose of 20 mg, its level in the blood plasma during the first 2 hours decreases rapidly, which is associated with the distribution process. After intramuscular injection, a level of 90% or more of the maximum concentration is reached after at least 15 minutes. With the recommended regimen of 20 mg per day, the equilibrium concentration in the blood plasma is reached within 10-15 days.

Composition

1 bottle contains tenoxicam 20 mg

1 ampoule with solvent contains 2 ml of water for injections.

Indications

To relieve pain and inflammation in osteoarthritis and rheumatoid arthritis.

For the short-term treatment of acute diseases of the musculoskeletal system, including sprains, dislocations and other soft tissue injuries.

Application

20 mg once a day during the first 1-2 days of treatment. Before use, the contents of the bottle must be dissolved in 2 ml of water for injections, which is included in the set of the medicinal product. The duration of tenoxicam treatment of acute disorders of the musculoskeletal system usually does not exceed 7 days. In exceptional cases, the duration of therapy can be extended up to 14 days. The drug is intended for intravenous and intramuscular use.

Store the bottles in their original package at a temperature not exceeding 25°C. Do not freeze. Keep out of the reach of children.